Science
The Human Body
Conceptual
12–14 yrs
DNA & Genes
DNA与基因
Description
Describe the double helix structure of DNA (base pairs, complementarity), explain how genes are sections of DNA that code for proteins, introduce the central dogma (DNA → mRNA → protein) conceptually, and discuss the ethical implications of CRISPR gene editing — including potential benefits (genetic disease treatment) and concerns (germline editing, 'designer babies')
Mastery Evidence
- Describes DNA as a double helix with four bases (A, T, C, G) where A pairs with T and C pairs with G
- Explains that a gene is a section of DNA that codes for a specific protein, and that proteins carry out most of the body's functions
- Describes CRISPR as a molecular tool that can cut and edit DNA sequences, and raises at least two distinct ethical considerations about its use in humans
Assessment Prompt
If your child heard that scientists have edited a human gene to prevent a hereditary disease, could they explain what DNA actually is, how genes work, and why some people think editing human DNA raises serious ethical questions?
Prerequisites 1
Chromosomes, Genes & DNA
DNA结构与复制依赖于对染色体和孟德尔遗传学的理解